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CardiaX

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About The Test

How To Prepare For The Test

Information

CardiaX aims to reduce the prevalence of heart disease and associated conditions by empowering you with a vital resource for early risk detection and enhanced focus on primary prevention. Determine if your unique genes are playing a role in your heart health so you can make choices for your heart health today.

Description

CardiaX is a novel genetic panel that includes the most relevant genes to cardiovascular functions including atherosclerosis, abnormal cholesterol production, hypertension, stroke risk, and even risk for heart attack. This panel provides important information that can affect your health choices and primary prevention strategies. Test, and don’t guess, by using CardiaX.

Symptoms and risk factors

CardiaX may be an appropriate test to run if you have or are suspected of having any of the following symptoms or conditions
  • Irregular heartbeat
  • High blood pressure

Is this test right for me?

CardiaX is a comprehensive and novel genetic panel of mutations associated with common cardiovascular risks. You may benefit from CardiaX is you have been diagnosed with or have risk for atherosclerosis, abnormal cholesterol production, hypertension, stroke risk, and risk for heart attack. This panel of genetics can aid your healthcare provider in customizing your treatment protocols based on your unique genetics.

How accurate is this test?

CardiaX from Vibrant wellness achieves 100% accuracy due to our proprietary technology. As a result, you can have total confidence in this panel.

How should I prepare for this test?

There is no special preparation before you have your blood drawn for CardiaX.

More Details

Risk Scores

  • Reynolds Risk Score
  • Framingham Risk Score

 

Metabolic Risk Markers

  • HbA1c
  • Glucose
  • Glycated Serum Protein
  • Insulin
  • C-Peptide
  • HOMA-IR
  • Adiponectin
  • TMAO
  • L-Carnitine
  • Ferritin
  • Leptin
  • Sodium
  • Potassium
  • Chloride
  • Carbon Dioxide
  • Glucose (Renal)
  • BUN
  • Creatinine
  • eGFR
  • eGFR (African American)
  • BUN/Creatinine Ratio
  • Serum Osmolality
  • Uric Acid
  • Cystatin C
  • ALT
  • AST
  • GGT
  • Bilirubin (Total)
  • Protein (Total)
  • Alkaline Phosphatase

 

Lipids & Ratios

  • Lipids
  • Total Cholesterol (TC)
  • Triglycerides (TG)
  • HDL Direct
  • Non-HDL-C
  • LDL Direct
  • Small Dense LDL (sdLDL)
  • Lipoprotein(a)
  • Apolipoprotein A-1
  • Apolipoprotein B
  • Lipid Ratios
  • TC/HDL-C
  • TG/VLDL-C
  • ApoB/ApoA-1
  • HDL-C/TG

 

Ceramides & Ratios

  • Cer(d18:1/16:0)
  • Cer(d18:1/18:0)
  • Cer(d18:1/24:1)
  • Cer(d18:1/16:0) / Cer(d18:1/24:0)
  • Cer(d18:1/18:0) / Cer(d18:1/24:0)
  • Cer(d18:1/24:1) / Cer(d18:1/24:0)

 

Sterols

  • Sterol Balance Score
  • Desmosterol
  • Lathosterol
  • Beta-Sitosterol
  • Campesterol

 

Redox Risk Markers

  • 8-OHdG
  • F2-Isoprostane
  • Malondialdehyde
  • Nitrotyrosine
  • Chlorotyrosine

 

Omega Fatty Acids

  • EPA
  • DPA
  • DHA
  • Linoleic Acid (LA)
  • Arachidonic Acid (AA)
  • AA/EPA Ratio
  • Omega-3 Index

 

Inflammation Markers

  • hsCRP
  • Homocysteine
  • IL-6
  • TNF-α
  • Omega-6 Total
  • Omega-3 Total

 

Endothelial Dysfunction Markers

  • ADMA
  • SDMA
  • Homoarginine
  • Arginine
  • Citrulline
  • Arginine/ADMA Ratio
  • Arginine/SDMA Ratio
  • Choline

 

Macrophage & Plaque Markers

  • Myeloperoxidase (MPO)
  • PLAC
  • Oxidized LDL (oxLDL)

 

Cardiac Stress & Clotting Risk Markers

  • NT-proBNP
  • Troponin-T
  • Creatine Kinase

 

Lipid Metabolism & Transport Genes

  • TCF7L2 – rs7903146, rs12255372
  • GCKR – rs780094
  • ANGPTL3 – rs1748195
  • ANGPTL4 – rs2967605
  • LPL – rs328, rs7007797, rs264,
  • rs320
  • GPIHBP1 – rs72691625
  • ZNF259 – rs964184
  • APOA5 – rs2075291, rs662799,
  • rs3135506
  • APOC3 – rs5128, rs138326449
  • SCD1 – rs508384, rs2167444
  • SCARB1 – rs4238001, rs5888
  • LCAT – rs2292318
  • APOA1 – rs632153, rs670
  • LPA – rs10455872, rs3798221,
  • rs6415084, rs7770628, rs3798220
  • MTP – rs1800591
  • SORT1 – rs599839
  • LDLR – rs688, rs72658855
  • LDLRAP1 – rs12071264
  • PCSK9 – rs562556, rs45613943
  • APOB – rs6752026, rs693,
  • rs515135
  • APOE – rs429358, rs7412
  • SIDT2 – rs17120425
  • CETP – rs1532624, rs247616,
  • rs708272
  • APOA2 – rs5082
  • CYP27A1 – rs4674344

 

Vascular Function & Blood Pressure Genes

  • NOS2 – rs1800482, rs3730017
  • NOS1 – rs1879417
  • NOS3 – rs1549758, rs2070744,
  • rs3918226, rs1799983
  • CORIN – rs2271037, rs3749585,
  • rs75770792 (T555I), rs111253292
  • (Q568P)
  • CYP4A11 – rs9332982, rs1126742
  • CYP4F2 – rs2108622
  • CYP11B2 – rs1799998
  • ADD1 – rs4961
  • EDN1 – rs5370
  • PHACTR1 – rs12526453, rs169713
  • 9p21 region – rs10116277,
  • rs4977574, rs1333049, rs10757278,
  • rs2383207, rs2383206
  • MTHFR – rs1801133, rs1801131
  • COMT – rs4680
  • CD36 – rs1761667
  • ADR-B2 – rs1042714
  • SMARCA4 (BRG1) – rs1122608
  • KCNK5 – rs10947789
  • KCNE2 – rs9982601
  • ZC3HC1 – rs11556924
  • VEGF-A – rs2010963
  • AGTR1 – A1166C
  • ACE – rs4343, rs4646994
  • AGT – rs699, rs4762, rs5051
  • 4q25 – rs2200733, rs10033464
  • GLUL – rs10911021

 

Pharmacogenomic Variants

  • CYP3A5 – 6986A>G (rs776746)
  • BCRP (ABCG2) – 421C>A
  • (rs2231142)
  • SLCO1B1 – rs4149056, c388A>G
  • (rs2306283)
  • CYP2C9 – rs1057910, -1188T>C
  • (rs4918758)
  • KIF6 – rs20455
  • OCT2 (SLC22A2) – rs7757336,
  • rs201919874
  • HO1 – rs2071746
  • COX-1 – rs1330344
  • CYP2C19*2 – rs4244285
  • AT1R – rs5182
  • BDKRB2 – rs1799722
  • PNPLA3 – rs738409
  • DGAT2 – rs1944438
  • NQO1 – rs1800566
  • CYP1A2 – rs762551

 

Pharmacogenomic Variants

  • CYP3A5 – 6986A>G (rs776746)
  • BCRP (ABCG2) – 421C>A
  • (rs2231142)
  • SLCO1B1 – rs4149056, c388A>G
  • (rs2306283)
  • CYP2C9 – rs1057910, -1188T>C
  • (rs4918758)
  • KIF6 – rs20455
  • OCT2 (SLC22A2) – rs7757336,
  • rs201919874
  • HO1 – rs2071746
  • COX-1 – rs1330344
  • CYP2C19*2 – rs4244285
  • AT1R – rs5182
  • BDKRB2 – rs1799722
  • PNPLA3 – rs738409
  • DGAT2 – rs1944438
  • NQO1 – rs1800566
  • CYP1A2 – rs762551

 

Inflammation & Oxidative Stress Genes

  • PON1 – rs662
  • ILR-6 – rs4845625
  • GPX1 – rs1050450
  • MPO – rs2107545
  • LIPA – rs1412444, rs2246833
  • ALDH2 – rs671
  • HDAC9 – rs2023938
  • CDKN2B-AS1 – rs10757274

 

Clotting & Thrombosis Genes

  • PLG – rs4252120
  • Prothrombin – rs1799963,
  • rs3136516
  • Factor V Leiden – rs6025
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