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COVID-19 Antibody Test | Spike & Nucleocapsid

If you’ve been exposed to COVID-19 or vaccinated, your body produces antibodies as part of your immune response. The test provides a numerical value that indicates whether or not you may have antibodies to COVID-19.

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Spike COVID-19 Antibody Test

Individuals who have been vaccinated with an mRNA vaccine may be positive with this test; past infection may also produce a positive result. The clinical significance of a positive antibody result for individuals who have received a COVID-19 vaccine is unknown, in part because the test’s performance characteristics have not been established for that population.

It is not known how long antibodies persist following infection and if the presence of antibodies confers protective immunity. This assay should not be used to diagnose acute SARS-CoV-2 infection.

Nucleocapsid COVID-19 Antibody Test

A positive result indicates an immune response to a recent or prior infection with SARS-CoV-2.

This test would not be expected to detect an immune response to an mRNA vaccine. It is unknown for how long antibodies persist following infection or if the presence of antibodies confers protective immunity. This assay should not be used to diagnose acute SARS-CoV-2 infection.

What is a semi-quantitative COVID-19 antibody test?

If you’ve been exposed to COVID-19 or vaccinated, your body produces antibodies as part of your immune response. The tests provides a numerical value that indicates whether or not you may have antibodies to COVID-19.

      • The results will be a numerical value above or below 1.00.
      • These tests cannot tell you if you have an active infection.
      • These tests should not be used to determine the level of immunity you may have.
      • Consult your healthcare provider for guidance on how to interpret your test results.
      • Regardless of your test results, it is important to continue to follow public health recommendations.

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Flatten the Curve

The COVID-19 Antibody Test, also known as a serology test, may help identify if you were previously exposed to the virus. Currently, the FDA allows antibody testing with the following important clarifications:

Frequently Asked Questions

  • Fever
  • Cough
  • Shortness of breath
  • Chills
  • Shaking with chills
  • Loss of taste or smell
  • Muscle pain
  • Headache
  • Sore throat

IgG antibodies are believed to appear 3-4 weeks after infection.

When IgG antibodies are present, it often indicates a past infection but does not exclude recently infected patients who are still contagious. It is unknown how long  IgG antibodies to SARS-CoV-2 will remain present in the body after infection and if they confer immunity to infection.

According to the Centers for Disease Control and Prevention, “Serologic test results have limitations that make them less than ideal tools for diagnosing people who are sick.”