Ceruloplasmin is a protein in the blood that can have different levels depending on a person’s health. When the levels of this protein go down, it might indicate several health issues:
Wilson’s Disease: A rare condition where copper builds up in the body.
Fulminant Liver Failure: A severe and sudden failure of the liver.
Intestinal Malabsorption: When the intestines can’t absorb nutrients properly.
Renal Failure with Proteinuria: Kidney failure that also involves the loss of protein in urine.
Chronic Active Hepatitis: A long-term inflammation of the liver.
Malnutrition: Not getting enough nutrients from food.
On the other hand, higher levels of ceruloplasmin might be seen in different conditions:
Primary Biliary Cirrhosis: A disease where the bile ducts in the liver are slowly destroyed.
Pregnancy (First Trimester): Early stages of pregnancy can increase ceruloplasmin levels.
Oral Contraceptive Use: Taking birth control pills can raise these levels.
Acute Inflammatory Conditions: Since ceruloplasmin is an acute phase reactant, its levels can go up when there is inflammation in the body.
